Gamble Madsen is originally from Claremont, California and specializes in the visualization of Christian theology in medieval and Renaissance contexts. She attended the University of Southern California as an undergraduate and graduate student, ultimately earning a PhD in Medieval Art History (dissertation: images of the Trinity associated with Peter Lombard's "Commentary on Psalm 109 [France, c.1160]").

She also holds a degree in Museum Studies from George Washington University, and has worked in collections management for institutions in New York (Lowy Fine Art) and Los Angeles (LACMA). She came to MPC in 2012 and currently teaches surveys in Western and Asian Art along with a course focused on the Renaissance period. She has presented research in medieval and early Renaissance visual culture at conferences in the U.S. and the U.K., and has recently published an article examining medieval representations of Job within Brill's "Companions to the Christian Tradition" series.